Generation of 20 human induced pluripotent stem cell lines from patients with focal segmental glomerulosclerosis (FSGS)
نویسندگان
چکیده
Focal segmental glomerulosclerosis (FSGS) is a major cause of familial nephrotic syndrome. We generated 20 induced pluripotent stem cell lines from patients diagnosed with FSGS. The iPSC include 8 female and 12 male cover donor age range 31 to 78. were peripheral blood mononuclear cells by integration-free reprogramming using Sendai virus vectors. Cell fully characterized regarding their pluripotency differentiation potential, quality controlled for karyotypic integrity, identity clearance represent valuable tool disease modelling drug development
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2021
ISSN: ['1876-7753', '1873-5061']
DOI: https://doi.org/10.1016/j.scr.2021.102406